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99% Pure Synthetic Tetrapeptide AC-Sdkp Peptide Raw Powder Goralatide Seraspenide Peptide Powder AC-Sdkp for Anti-Inflammatory and Antifibrotic
| Price | $200.00 |
|---|---|
| Min Order | 2 G |
| Availability | In Stock |
| Shipping From | Hubei, China |
| Popularity | 509 people viewed |
CAS No.:
67727-97-3
Formula:
C16h30n4o4
EINECS:
N/a
Type:
Synthesis Material Intermediates
Appearance:
Powder
Quality:
Refined
Colour:
White
Content:
Standard
Usage:
Laboratory Reagents
Source:
Dry Powder
Habit Appellation:
Fine Chemicals
Application:
Scientific Research
Property:
Protein and Peptide
Classification:
Research Peptides
Note:
No Tfa Salt
From:
Authoried Regluar Workshop
Raw Powder:
1g/Bottle
Attention:
Research Use Only
Trademark:
Hoconbio
Transport Package:
Customized
Specification:
1G/Bottle 2mg/5mg/10mg per vial
Origin:
China
Product Description
99% Pure Synthetic Tetrapeptide Ac-SDKP Peptide Raw Powder Goralatide Seraspenide Peptide Powder Ac-SDKP For Anti-inflammatory And Antifibrotic
| Product Name | Ac-SDKP |
| CAS NO. | N/A |
| Other name | goralatide / seraspenide |
| Appearance | White powder |
| Purity | 98% HPLC |
| Application | Research peptides |
| Shelf Life | 24 Months |
| Storage | Store at a temperature of 2-8 degrees, protected from light. |
Ac-SDKP peptide (also known as seraspenide or goralatide)
The synthetic tetrapeptide Ac-SDKP, also called seraspenide or goralatide, has the chemical structure 1-(N2-(N-(N-acetyl-L-seryl)-L-alpha-aspartyl)-L-lysyl)-L-proline, the molecular formula C20H33N5O9, and a molecular weight of 487.50412 dalton. This tetrapeptide is involved in angiogenesis and the regulation of the immune response by blocking the proliferation of lymphocytes.
Ac-SDKP is a natural tetrapeptide with anti-inflammatory and antifibrotic properties. It has been widely distributed in mammalian organs, plasma, urine, and circulating mononuclear cells. The peptide is hydrolyzed by angiotensin-converting enzyme (ACE) and has a short half-life of 4.5 min in the circulation. Treatment with ACE inhibitors significantly increases plasma concentration of Ac-SDKP, and some of the ACE inhibitors protective effects were reported to be mediated by the increases in Ac-SDKP concentrations. In animal diseases with hypertension, as well as cardiovascular and kidney disease, Ac-SDKP reduces inflammatory cell infiltration and collagen deposition in the heart, kidney, lung, and liver. The peptide has potential applications in the treatment of various inflammatory and fibrotic diseases.
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