$15.00
10 kg (MOQ)
Bonding Agent Cyanoethylated Polyamine Hx-878 CAS No 68412-46-4
Getchem Co., Ltd.
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Manufacturer Supply Improve Metabolism Ipa Purity 99.9% Peptides
| Price | $10.00 |
|---|---|
| Min Order | 1 kits |
| Availability | In Stock |
| Shipping From | Chongqing, China |
| Popularity | 295 people viewed |
Model NO.:
IPA
CAS No.:
330
Formula:
Vdsds
EINECS:
330
Type:
Pharmaceutical Intermediates
Appearance:
Powder
Quality:
Janoshik
Colour:
White
Content:
99%
Actual Standard:
Exceed Content
Sterile:
Yes
Test Report:
Janoshik
Private Customization:
Yes
Payment Method:
Support All Payment Methods
Shipping Time:
7-12 Days
Resend:
Different Ways in Different Regions
Hot Products:
Ipa
Trademark:
Cocer
Transport Package:
Concealed Transportation
Specification:
5mg 10mg
Origin:
China
HS Code:
3001200010
Product Description
| Purity | 99%+ | Private customization | 2mg 5mg 10mg 15mg 20mg 30me etc. | |
| Cleanliness | Sterile | Transportation time | 7-15days | |
| Actual peptide content | Exceed the standard | Disguise | Can provide | |
| Test Report | COA HPLC Third party testing | Resend policy | According to different countries | |
| Customized top color | Red Yellow Blue Black Purple White Green | Payment method | Bank Transfer BTC USDT Paypal |
The development and pharmacology of a new potent, IPA, is described. IPA is a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2), which displays high releasing potency and efficacy in vitro and in vivo. As an outcome of a major chemistry programme, IPA was identified within a series of compounds lacking the central dipeptide Ala-Trp. In vitro, IPA released from primary rat pituitary cells with a potency and efficacy similar. A pharmacological profiling using antagonists clearly demonstrated that IPA, stimulates release via a-like receptor. In anaesthetised rats, IPA released with a potency and efficacy comparable. In conscious swine, IPA released. displayed higher potency but lower efficacy . The specificity for release was studied in swine. None of the secretagogues tested affected FSH, LH, PRL or TSH plasma levels. Administration of both resulted in increased plasma levels of and cortisol. Very surprisingly, IPA did not release or cortisol in levels significantly different from those observed following stimulation. This lack of effect on and cortisol plasma levels was evident even at doses more than 200-fold higher than the ED50 for release. In conclusion, IPA is the first -receptor agonist with a selectivity for release similar to that displayed. The specificity of IPA makes this compound a very interesting candidate for future clinical development.
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