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Olaparib, Olaparib (AZD-2281) , Antitumor Raw Materials, Olapani Intermediate
| Price | $2100.00 |
|---|---|
| Min Order | 1 kg |
| Availability | In Stock |
| Shipping From | Shanghai, China |
| Popularity | 386 people viewed |
Model NO.:
10kg
Powder:
Yes
Customized:
Non-Customized
Certification:
GMP, USP
State:
Solid
Purity:
>99%
Trademark:
OEM
Transport Package:
Bags
Specification:
1kg/10kg
Origin:
China
HS Code:
2934999099
Product Description
Chinese name: Olapani
Chinese synonym: Olapani; Olapani, AZD2281; Olaparib; Olapani form bottom; Orapali
English name: Olaparib
English synonym: Olaparib; 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine; Olaparib(AZD-2281); Azd 2281; Azd2281; Azd-2281; Ku-0059436; 4-[3-(4-Cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one Olaparib
CAS number: 763113-22-0
Molecular formula: C24H23FN4O3
Molecular weight: 434.469
Appearance: White powder
Purpose: Olaparib is a novel inhibitor of poly ADP ribose polymerase (PARP), including PARP1, PARP2, and PARP3. PARP mediates a DNA repair mechanism and plays an important role in DNA damage repair and cell apoptosis. Therefore, Olapanide specifically acts on the DNA damage repair mechanism of targeted cells by attacking the key loopholes in cancer cells carrying BRCA1 and BRCA2 mutations, which can be used for the maintenance treatment of patients with recurrent severe ovarian cancer who are sensitive to platinum drugs and have breast cancer susceptibility gene (BRCA) mutations.
Chinese synonym: Olapani; Olapani, AZD2281; Olaparib; Olapani form bottom; Orapali
English name: Olaparib
English synonym: Olaparib; 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine; Olaparib(AZD-2281); Azd 2281; Azd2281; Azd-2281; Ku-0059436; 4-[3-(4-Cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one Olaparib
CAS number: 763113-22-0
Molecular formula: C24H23FN4O3
Molecular weight: 434.469
Appearance: White powder
Purpose: Olaparib is a novel inhibitor of poly ADP ribose polymerase (PARP), including PARP1, PARP2, and PARP3. PARP mediates a DNA repair mechanism and plays an important role in DNA damage repair and cell apoptosis. Therefore, Olapanide specifically acts on the DNA damage repair mechanism of targeted cells by attacking the key loopholes in cancer cells carrying BRCA1 and BRCA2 mutations, which can be used for the maintenance treatment of patients with recurrent severe ovarian cancer who are sensitive to platinum drugs and have breast cancer susceptibility gene (BRCA) mutations.
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