3.2% Citric Acid Sodium Vacuum, Single-Use Negative Pressure Vacuum Blood Collection Tube Sodium Citrate Tube Coagulation Tube, Blue Cap Glass Pet

The main function of the 3.2% sodium citrate blood collection tube is to prevent blood coagulation and maintain the stability of blood samples for various blood tests and analyses. The principle of action of sodium citrate as an anticoagulant is as follows:

Chelating calcium ions: Citrate ions from sodium citrate can tightly bind with calcium ions in the blood, forming a soluble citric acid-calcium complex. Calcium ions are key components in the blood coagulation process, and by chelating calcium ions, sodium citrate effectively prevents blood coagulation.

Preventing thrombin generation: Since calcium ions play an important role in the coagulation process, sodium citrate indirectly inhibits thrombin generation by reducing available calcium ions, further preventing blood coagulation.

Maintaining blood liquidity: In vitro, sodium citrate maintains the liquid state of blood samples, which is crucial for accurate blood testing.

Applicable to specific tests: 3.2% sodium citrate tubes are commonly used for coagulation time determination and erythrocyte sedimentation rate (ESR) tests. For coagulation time determination, the ratio of sodium citrate to blood sample is 1:9; for ESR tests, the ratio is 1:4. Both tests require ensuring that blood samples do not clot to obtain accurate results.

When using 3.2% sodium citrate tubes, it is essential to consider the following points:

Gentle mixing: After obtaining a blood sample, gently mix the sample thoroughly with the anticoagulant to ensure that the blood does not clot. Avoid excessive handling: Excessive shaking may cause red blood cell rupture, affecting test results. In summary, 3.2% sodium citrate tubes play an important role in clinical laboratory testing, ensuring the stability of blood samples and the accuracy of test results.