Adenosine Triphosphate CAS 56-65-5 5'-Deoxyadenylate Triphosphate

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Ningbo Surest Chemical Co., Ltd.

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SUREST-304
56-65-5
C10h16n5o13p3
200-283-2
CCIC, CIQ, ISO
≥99%
Adenosine Triphosphate
Food Grade
2 Years
Available
507.18
144°c
D22 -26.7° (C = 3.095)
Surest
1kg/Bag or 25kg/Bag
98%min
China
2934993090
Product Description
Product Description
 
NameAdenosine triphosphate
Synonyms5'-Deoxyadenylate triphosphate; Adenosine 5'-triphosphate; [(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate
 
Molecular Structure 
Molecular FormulaC10H16N5O13P3
Molecular Weight507.18
CAS Registry Number56-65-5
EINECS200-283-2
 






 
Main Uses:

 

5' -adenosine triphosphate is a metabolite of adenosine, a multifunctional nucleoside triphosphate that is used in cells as an intracellular energy transfer coenzyme to transport chemical energy within the cell for metabolism.

ATP(5mM;1hour)co-treatmentwithLPS(1μg/mL)hasasynergisticeffectontheactivationoftheNLRP3inflammasomeinHGFs.ATP(2mM;0.5-24houChemicalbookrs)inducessecretionofIL-1β,KCandMIP-2fromBMDMsinacaspase-1activation-dependentmanner.ATPpromotesneutrophilchemotaxisinvitro.

ATP(50mg/kg;i.p.)protectsmiceagainstbacterialinfectioninvivo.ATPinducesthesecretionofIL-1β,KCandMIP-2andneutrophilsrecruitmentinvivo.AnimalModel:Four-weeChemicalbookk-oldKunmingmice(18-22g)Dosage:50mg/kgAdministration:Intraperitonealinjection,beforebacterial(E.coli)challengeResult:Protectedmicefrombacterialinfection.

 

 

 





 
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