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Lightweight Nose-only Inhalation Exposure System (Model NIES-Lite)
The NIES-Lite system is a cutting-edge, compact inhalation exposure solution designed for small-scale inhalation studies. Ideal for respiratory drug efficacy and pharmacokinetic trials, as well as respiratory disease modeling, this system offers unmatched precision, efficiency, and flexibility. With a footprint of just 0.3 square meters and a capacity to handle 10 to 30 animals, the NIES-Lite system is designed for labs looking to maximize space without sacrificing performance.
Typical Applications:
- Small-scale inhalation pharmacodynamics/pharmacokinetics (PD/PK) studies
- Respiratory disease modeling
- Safe and controlled aerosol exposure
Key Features
| Feature | Description |
| System Footprint | Compact design with a 0.3 square meter footprint. |
| Deployment Options | Two flexible deployment methods to fit various laboratory setups. |
| Animal Capacity | Supports 10-30 animals per study. |
| Reliability | Over 10,000 hours of continuous operation without failure. |
| Compatibility | Compatible with biosafety cabinets for enhanced safety. |
| Cost Efficiency | High cost-effectiveness with lifelong technical support. |
System Configuration:
| Component | Description |
| Cabinet Unit | Optional - Users may opt to use their own biosafety cabinets. The system is lightweight and can be installed in standard biosafety cabinets or on lab benches. |
| Exposure Unit | 2.1 Exposure Chamber: Made from SUS316L medical-grade stainless steel, it accommodates 10 animals per layer, expandable to 30. Supports natural inhalation conditions for rats, mice, and guinea pigs. Ensures minimal sample loss and high dosing efficiency. |
| 2.2 Rodent Restrainers: Designed for safe and efficient animal restraint during exposure. | |
| Aerosol Generation Unit | Supports various aerosol nebulizers and dust generators, configurable to meet specific research needs. |
| Sampling and Analysis Unit | Offers multiple aerosol sampling devices. (User-configurable) |
| Control/Monitoring System | Digital control system with a touchscreen interface for managing aerosol generation, dilution, and nebulizer control. The Inhalogic CTU-Lite Control Unit precisely controls air flow to maintain dynamic aerosol exposure. Environmental parameters like temperature, humidity, and gas concentrations are measurable with optional probes. (User-configurable) |
| Exhaust Unit | The Inhalogic ASU Lite Waste Gas Scavenging Unit filters and safely exhausts contaminated aerosol samples. It features a built-in vacuum pump, with exhaust air flow measured by a mass flow sensor and controlled by a proportional valve. |
| Air Compressor | Optional - Silenced Medical Grade Oil-free Air Compressor available, including air compressor, air dryer, condensate drainage, oil separator, and filter. (User-configurable; customers may also use local air compressors) |
| Advantage | Details |
| Precision Exposure | Concentration error between animal ports is less than ±8%. |
| Comprehensive Control | Digital control of aerosol generation, dilution, and exhaust flows. |
| Waste Gas Management | Effective waste gas treatment for safe emissions. |
| Environmental Monitoring | Optional sensors for temperature, humidity, O2, and CO2 levels. |
| Customizable Configuration | Various aerosol nebulizers, dust generators, and sampling devices. |
Why Choose NIES-Lite?
The NIES-Lite system combines advanced technology with user-friendly operation, making it an excellent choice for laboratories focused on small-scale inhalation studies. Its robust design ensures reliable performance, while its compact size makes it a practical addition to any research facility. With comprehensive support, customizable configurations, and certified quality through CE and ISO certifications, NIES-Lite is the ideal solution for precise and efficient inhalation exposure experiments.
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