| Items | Standards | Test Result |
| Physical Analysis | ||
| Description | Sophora Japonica Extract | Complies |
| Assay | Rutin | 95% |
| Mesh Size | 80 mesh | Complies |
| Ash | ≤ 0.5% | 0.43% |
| Loss on Drying | ≤ 8.5% | 6.4% |
| Chemical Analysis | ||
| Heavy Metal | ≤ 10.0 mg/kg | Complies |
| Pb | ≤ 3 mg/kg | Complies |
| As | ≤ 2 mg/kg | Complies |
| Cd | ≤ 1 mg/kg | Complies |
| Hg | ≤ 0.1 mg/kg | Complies |
| Microbiological Analysis | ||
| Total Plate Count | ≤ 1000cfu/g | Complies |
| Yeast&Mold | ≤ 100cfu/g | Complies |
| E.coil | Negative | Negative |
| Salmonella | Negative | Negative |
The main functions of rutin extracted from Sophora japonica buds are as follows:
Rutin is a natural antioxidant that can scavenge excessive free radicals in the body, such as superoxide anion radicals and hydroxyl radicals. These free radicals can damage cell membranes, proteins, and nucleic acids, leading to a variety of diseases, including those related to aging. Rutin protects cells from oxidative stress by providing hydrogen atoms to neutralize free radicals. For example, in some in - vitro cell experiments, the addition of rutin can significantly reduce cell damage induced by oxidative stress and increase cell survival rate.
- Reducing capillary permeability and fragility: Rutin can enhance the resistance of capillaries and maintain their normal permeability. This helps prevent capillary rupture and bleeding and is effective in preventing and improving diseases caused by fragile capillaries, such as purpura.
- Antithrombotic effect: It can inhibit platelet aggregation and reduce the risk of thrombosis. Platelet aggregation is a crucial step in thrombosis, and rutin exerts its antithrombotic effect by inhibiting the relevant signaling pathways and reducing platelet activity.
- Antihypertensive effect: Rutin can dilate blood vessels and reduce peripheral vascular resistance, thereby lowering blood pressure. Some animal experiments have shown that rutin can reduce the blood pressure of hypertensive model animals to varying degrees.
Rutin can inhibit the release of inflammatory factors such as interleukin - 1β (IL - 1β), interleukin - 6 (IL - 6), and tumor necrosis factor - α (TNF - α). These inflammatory factors play a key role in the inflammatory response. By inhibiting their release, rutin can alleviate the inflammatory response. In some inflammatory disease models, such as arthritis models, rutin can reduce joint swelling and pain and improve inflammatory symptoms.
Although rutin cannot directly serve as an anti - tumor drug, it can play an adjuvant role in tumor treatment. It can enhance the body's immunity and improve the body's immune surveillance ability against tumor cells. At the same time, the antioxidant effect of rutin also helps to reduce the damage to normal tissues during chemotherapy and radiotherapy. For example, in some in - vitro experiments of tumor cells, the combination of rutin and chemotherapy drugs can improve the killing effect of chemotherapy drugs on tumor cells and reduce the toxicity of chemotherapy drugs to normal cells.
Rutin can protect liver cells from damage and promote the regeneration of liver cells. It can reduce oxidative stress and inflammatory response in the liver and has a certain improvement effect on some liver diseases, such as drug - induced liver injury and fatty liver. Research has found that rutin can regulate the activities of some enzymes in the liver, such as glutathione peroxidase (GSH - Px) and superoxide dismutase (SOD), and enhance the antioxidant capacity of the liver.

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