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Coleus Forskohlii Extract Powder is derived from the roots of the Coleus Forskohlii plant, which is native to India, Thailand, and Nepal. The active ingredient in this extract is Forskolin, a diterpene compound known for its various health benefits. Here is a detailed introduction to Coleus Forskohlii Extract Powder:
Scientific Name and Synonyms
- Scientific Name: Coleus forskohlii (Willd.) Briq.
- Synonyms: Plectranthus barbatus, Plectranthus forskalaei, Plectranthus forskohlii, Plectranthus kilimandschari, Plectranthus grandis
Appearance
- The extract is typically a yellow-brown fine powder .
Active Ingredient
- Forskolin (C22H34O7) is the primary active compound. It has a molecular mass of 410.501 and a CAS number of 66428-89-5 .
Health Benefits
Weight Loss
- Forskolin has been found to release stored fat from fat cells without causing a calorie deficit. It can help in weight management by increasing lipolysis and preventing weight gain in rats fed a high-fat diet .
Asthma
- Coleus Forskohlii Extract has been used traditionally to treat asthma. It relaxes the muscles of the airways and increases lung capacity, making it easier to breathe .
Heart Health
- The extract can help lower blood pressure and improve heart health by increasing blood flow and reducing inflammation .
Bone Density
- Forskolin has the potential to increase bone density, making it a potential treatment for osteoporosis .
Anti-inflammatory and Antioxidant Properties
- Coleus Forskohlii Extract has been shown to lower thromboxane B2 and superoxide levels, inhibit macrophage activation, and reduce inflammation. Its properties are comparable to those of vitamin E .
Mechanism of Action
- Forskolin directly activates adenylate cyclase (AC), which increases the concentration of cyclic AMP (cAMP) in various tissues. This increase in cAMP levels is involved in multiple cellular functions, including the regulation of hormone release, cell growth, and metabolism
Item | Specification | Method Result | |
Appearance | Fine Powder | Organoleptic Conforms | |
Color | Light yellow brown powder | Organoleptic Conforms | |
Odour | Characteristic | Organoleptic Conforms | |
Mesh Size Drying Method | 100% through 80% mesh size spray drying | USP32<786> Conforms spray drying Conforms | |
Ash Loss on Drying | ≤5.0% ≤5.0% | Eur.Ph.6.0[2.4.16] 2.26% Eur.Ph.6.0[2.4.16] 3.39% | |
Contaminants |
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Pesticides Residue | Meet USP32<561> | USP32<561> Conforms | |
Lead(Pb) | ≤3.0mg/kg | Eur.Ph6.0<2.2.58>ICP-MS 2.0 | |
Arsenic(As) | ≤2.0mg/kg | Eur.Ph6.0<2.2.58>ICP-MS 1.7 | |
Cadmium(Cd) | ≤1.0mg/kg | Eur.Ph6.0<2.2.58>ICP-MS 0.8 | |
Mercury(Hg) | ≤0.1mg/kg | Eur.Ph6.0<2.2.58>ICP-MS 0.06 | |
Microbiological |
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Total Plate Count | ≤10000cfu/g | USP30<61> Conforms | |
Yeast &Mold | ≤500cfu/g | USP30<61> Conforms | |
E.Coli. | Negative | USP30<62> Conforms | |
Salmonella | Negative | USP30<62> Conforms | |
