Audited Supplier
C57
RoHS, BRC, ISO, FDA, HACCP
HPLC-MS, GPC, HPLC, UV
Injection, Lotion, Suppository, Paste, Tablet, Capsule
Food, Health Care Products, Medicine
Powder
Colchicum Autumnale Extract
Colchicine
White Powder
98%
64-86-8
Available
Available
Adult
10g
Anti-Inflammatory
/
Foil Bag
98
China
Product Description
| Product Name | Colchicine |
| Appearance | White Powder |
| CAS NO. | 64-86-8 |
| Molecular Formula | C22H25NO6 |
| Storage | Keep in a cool, dry, dark location |
Colchicine unique mechanism of action and diverse therapeutic applications make it a useful medication in the management of specific inflammatory and cardiac conditions. However, its use should be carefully monitored due to potential side effects and interactions with other medications.
- Gout Treatment: Colchicine is primarily used in the management of gout, particularly during acute flares, to reduce inflammation and pain.
- Inflammatory Disorders: It has also been employed in the treatment of other inflammatory conditions, such as Behçet's disease and familial Mediterranean fever, where it helps to control recurrent inflammatory attacks.
- Cardiac Conditions: In certain cardiac conditions, such as pericarditis, colchicine can be used to decrease inflammation and prevent recurrence.
- Anti-Inflammatory Effects: Colchicine exerts its anti-inflammatory action by inhibiting the migration and phagocytosis of neutrophils, reducing the release of inflammatory mediators.
- Microtubule Disruption: At a cellular level, colchicine binds to tubulin, disrupting microtubule formation and function, which alters cellular permeability and inhibits cellular division and motility.
- Modulation of Immune Responses: By modulating immune responses and reducing the production of cytokines and chemokines, colchicine helps to control the immune-mediated inflammation associated with its therapeutic indications.
