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Hemin is a ferric compound acknowledged as a biologic iron source of high absorptivity and good effect for preventing and curing iron deficiency anemia in modern medicine. Hemin has no ferric smell. It does not stimulate stomach or intestines and has no toxicity or side effect. Even pregnant women and children are safe to take the medicine. Moreover, Hemin is directly absorbed by intestinal mucosa, with ahigh absorptivity more than 25%. Hemoglobin tent and erythrocyte quantity in the body can be increased within a short time after taking this medicine so that anemia is improved quickly. Now iron-supplement products with hemin authorized by Ministry of Health are in capsule, tablet and oral liquid. So hemin is the preferred material for natural iron-supplement food, drug and health products.
| Component item | Specification |
| Protein(%) | ≥65% |
| Fe(Iron)(%) | ≥2.0 |
| Ash (%) | ≤6.0 |
| Moisture(%) | ≤3.0 |
| Bacterium Number in a Gram(cfu/g) | ≤1000 |
| Coli group(per/100g) | Absent |
| Pathogenic Bacteria(Salmonella) | Absent |
| Pb (ppm) | ≤0.5 |
| As (ppm) | ≤0.3 |
| Hg (ppm) | ≤0.3 |
Heme iron: In 1930, German scientist Hans Fisher discovered the best substance for iron-deficiency anemia, organic porphyrin iron, with an absorption rate of up to 35%. Heme is an important component of hemoglobin, and its purified form in vitro is hemin (hemin). In the past, it was only known that heme iron can be directly absorbed by intestinal mucosal cells, but it is not known how it is absorbed. Now it is clear that heme iron is directly absorbed by duodenal and upper small intestinal mucosal cells in the form of metalloporphyrins to form endosomes. Absorption, iron ions are separated under the action of intracellular heme oxygenase and used by the body [21], and absorption is not affected by dietary types (protein, plant fiber, oxalic acid, tannic acid, plant fiber, etc.) Acid does not affect its absorption), no gastrointestinal irritation and other advantages, it is currently the best iron source. The absorption rate of ferrous sulfate is only 1%-3%, and it is severely irritating to the intestines and stomach, and has obvious toxic and side effects. In July 1983, the US FDA approved hemin as a medicine.
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