Audited Supplier
Tetracaine hcl Basic Information:
| Product name | Tetracaine hcl ( Tetracaine Hrdrochloride) |
| CAS No. | 136-47-0 |
| Molecular formula | C15H25ClN2O2 |
| Molecular weight | 300.82 |
| EINECS number | 205-248-5 |
| Melting point | 149°C |
| Storage condition | Room Temperature |
| Purity | >99% |
| Standard | Pharmaceutical Grade |
| Appearance | White or almost white crystal powder |
Lidocaine hydrochloride is metabolized rapidly by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. N-dealkylation, a major pathway of biotransformation, yields the metabolites monoethylglycinexylidide and glycinexylidide. The pharmacological/toxicological actions of these metabolites are similar to, but less potent than, those of Lidocaine hydrochloride. Approximately 90% of Lidocaine hydrochloride administered is excreted in the form of various metabolites, and less than 10% is excreted unchanged. The primary metabolite in urine is a conjugate of 4-hydroxy-2,6-dimethylaniline.
Lidocaine hcl is a local anesthetic and antiarrhythmic drug. Used for infiltration anesthesia, epidural anesthesia, surface anesthesia (including in the thoracoscopy or abdominal surgery for mucosal anesthesia) and nerve conduction block.
Lidocaine hcl is an amide local anesthetic.
With the dose increased, the role or toxicity increased, there is an anti-convulsive effect with sub-poisoning plasma concentration;
Blood concentration of more than 5μg ? ml-1 can occur convulsions.
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