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Minoxidil is one of the most effective treatments for hair loss is Minoxidil. Its unique properties stimulate the proliferation and differentiation of hair follicle epithelial cells, promote angiogenesis, and open potassium channels. This multi-pronged approach offers a holistic solution to hair loss, going beyond merely treating symptoms.
The Mechanism of Minoxidil
Minoxidil works through several mechanisms. First, it relaxes the smooth muscles of blood vessels, promoting blood flow and aiding hair growth. It also has the unique ability to end the resting phase of hair growth early, extending the active phase and promoting the transformation from the resting to the growth phase. Further, Minoxidil stimulates the proliferation of hair follicle cells, enhancing the transformation of vellus hair to terminal hair. It promotes angiogenesis, which increases the local blood supply and nutrient supply. Lastly, it can inhibit the infiltration of T lymphocytes around hair follicles and promotes the reopening of closed blood vessels.
(A)Minoxidil Powder can stimulate the proliferation and differentiation of hair follicle epithelial cells: the normal human hair follicle epithelial cells in different concentrations of minoxidil solution in the micro-molar concentration of minoxidil can stimulate hair follicle epithelial cell proliferation.
(B)Minoxidil Powder can promote angiogenesis: increase the local blood supply: hair growth depends on the hair nipple blood supply network nutrition, hair in the different growth cycle, vascular endothelial growth mRNA expression is different from the growth of vascular endothelial growth mRNA in the dermis Nipple cells were strongly expressed, but were less expressed during retrograde and resting periods.
(C)Minoxidil Powde can open potassium channels: potassium channel opening is an important step in regulating hair growth, animal models in vitro and in vivo experiments have shown that minoxidil is a potassium channel activator, can increase the permeability of potassium ions to prevent calcium ion flow Intracellular, resulting in decreased free calcium concentration in cells, while calcium ions, epidermal growth inhibit hair growth.
