High Quality Methylene Chloride CAS: 75-09-2

Rabbit transdermal: 810mg (24h), severe irritation.

Rats were inhaled 4.69g/m3 for 8h a day for 75 days without pathological changes. Increased exposure time, mild hepatic atrophy, steatosis, and cell infiltration.

Microbial mutagenicity: Salmonella typhimurium 5700ppm.

DNA inhibition: human fibroblast 5000ppm (1h) (continuous). ,

DNA damage: Hamster ovary 3000ppm.

Sister Chromatid Exchange: Hamster Lung 5000ppm (1h) (Continuity)

The lowest toxic dose (TCLo) of 1250ppm (7h) was given to rats 6-15d after pregnancy, resulting in malformation of musculoskeletal system and genitourinary system.

LC50:193mg/L (96h) (minnows, dynamic); 310mg/L (96h) (Minnows, static); 200-250 mg/L (96h) (bluegill sunfish, static); 224mg/L (48h) (Water flea); 256mg/L (96h) (Sugar Shrimp)

Aerobic biodegradation: 168~672h

Anaerobic biodegradation: 672 ~ 2688 h

non-biodegradability

Maximum wavelength range of photolysis: 220~250nm

Photooxidation half-life in air - high: 458~4584h

First-order hydrolysis half-life: 704a h

Other harmful effects

The substance is harmful to the environment and accumulates in groundwater. Special attention should be paid to aquatic life. Attention should also be paid to the pollution of the atmosphere.

product use

1. Used for grain fumigation and refrigeration of low pressure refrigerator and air conditioning unit.

2, used as solvent, extractant, mutagenic agent.

3, used in the electronics industry. Commonly used as a cleaning agent to remove oil.

4, used as dental local anesthetic, refrigerant, fire extinguishing agent, metal surface coating cleaning and degreasing agent.

5, used as an intermediate in organic synthesis.

environmental standards

Former Soviet Union: Maximum allowable concentration of hazardous substances in the air of workplace: 50 mg/m3

Maximum permissible concentration of hazardous substances in drinking water sources in China (to be promulgated) : 0.02 mg/L

China (GHZB1-1999) Surface Water Environmental quality Standard (Class I, , waters) : 0.005 mg/L

Maximum allowable concentration of hazardous substances in water bodies of the former Soviet Union (1975) : 7.5 mg/L

Japan (1993) Environmental standard (mg/L) : Ground water: 0.002; Waste water: 0.02; Soil leaching solution: 0.002; The olfactory threshold concentration is 150ppm.

Avoid droplet production and wear appropriate personal protective equipment during operation. Avoid releasing steam and fog droplets into the air of the work area. Operate in a specific area with good ventilation and take the minimum amount. Emergency response equipment should be available at all times to fight fires and deal with spills. Empty storage containers may still contain hazardous residues. Do not operate in the vicinity of welding, flame, or hot surfaces.

Store in a cool, dry, well ventilated place away from direct sunlight. Store away from heat source, flame and incompatibilities such as strong oxidant, strong acid and nitric acid. Store in a properly labeled container. Unused containers and empty drums should be tightly covered. Avoid damage to the container and inspect the tank regularly for defects such as breakage or spills. Containers are lined with galvanized or Phenolic resin to reduce the possibility of decomposition of methylene chloride. Limited storage. Post warning signs where appropriate. The storage area should be separated from the staff intensive work area and restricted access to the area. Use plastic pipes that are designated for use with substances to discharge toxic substances. The material could build up static electricity which could cause combustion. Store in a cool, dry, well ventilated place away from direct sunlight.