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Polyethylene glycol 400 is a polymer composed of ethylene glycol molecules connected by ether bonds, where the number of repeating units of ethylene glycol molecules is 400.
It is a colorless and transparent liquid, easily soluble in water, with a pH value of 5-7 in 1% aqueous solution and an average molecular weight between 300-500. The characteristics of this product are that it can be miscible with water in any proportion, is not easy to volatilize, and is used as a humidifier in various mixtures to absorb and retain moisture.
Appearance(25ºC) | Transparent liquid |
| Melting Point/Freezing Point (ºC): | 4~8 |
| Flash Point (ºC)( Closed Cup): | 240 |
| Vapor Pressure (KPa): | 10Pa (20ºC) |
| Relative Density(Water=1): | 1.13 |
| Decomposition Temperature(ºC): | 271 |
| Initial Boiling Point and Boiling Range (ºC): | >200 |
| Upper/lower explosive limits[%(v/v)]: | Upper limit: 6.9; Lower limit: 1.1 |
| Relative Vapour Density(Air=1): | >1 |
| Solubility: | Miscible with water |
| Auto-lgnition Temperature(ºC): | 360 |
| Reactivity | Contact with incompatible substances can cause decomposition or other chemical reactions. |
| Chemical Stability | Stable under proper operation and storage conditions. |
| Possibility of Hazardous Reactions | No information available |
| Conditions to Avoid | Incompatible materials, heat, flame and spark. |
| Incompatible Materials | No information available |
| Hazardous | Under normal conditions of storage and use, hazardous decomposition products |
It has a wide range of uses. It can be used as a plasticizer-wetting agent for films to enhance the strength and dimensional stability of films; it is used in the pharmaceutical industry to prepare ointments, emulsions, and ointments, etc., and can obtain a consistency similar to that of vaseline; in addition, it is also used as a lubricant and moisturizer in other industries.
PEG-400 is most suitable for making soft capsules. Due to its liquid nature and wide compatibility with various solvents, PEG400 is an excellent solvent and solubilizer. When vegetable oil is not suitable as an active ingredient carrier, PEG is the preferred solubilizing material. This is mainly because PEG is stable and not easily spoiled, and injections containing PEG are safe and stable when heated to 150 degrees Celsius. In addition, PEG with different high molecular weights can be mixed to make the mixture have good solubility and compatibility with drugs
