CHONDROITIN SULFATE FUNCTION
Chondroitin's functions depend largely on the properties of the overall proteoglycan of which it is a part. These functions can be broadly divided into structural and regulatory roles. However, this division is not absolute, and some proteoglycans have both structural and regulatory roles (see versican).
Chondroitin sulfate is a major component of extracellular matrix, and is important in maintaining the structural integrity of the tissue. This function is typical of the large aggregating proteoglycans: aggrecan, versican, brevican, and neurocan, collectively termed the lecticans.
As part of aggrecan, chondroitin sulfate is a major component of cartilage. The tightly packed and highly charged sulfate groups of chondroitin sulfate generate electrostatic repulsion that provides much of the resistance of cartilage to compression. Loss of chondroitin sulfate from the cartilage is a major cause of osteoarthritis.
Appearance | White to Off-white Free Flowing Powder |
Clarity and Color of Solution | 0.35 Max at 420nm |
Specific Rotation | -20.0 - -30.0 |
Chondroitin Sulfate Assay(CPC) | 85% Min by CPC |
Loss On Drying | 10% Max |
PH | 5.5---7.5 |
Bulk Density | 0.6g/ml Min |
Particle Size | 100%through 80mesh |
Content of Protein | 6.0% Max (Dried Basis) |
Residue On Ignition | 20%---30% |
Heavy Metals | 20PPM Max |
Total Plate Count | 1,000cfu/g Max |



