Audited Supplier
480-41-1
CAS No: 480-41-1
C15h12o5
CAS No: 480-41-1
Plant Extract
Powder
Refined
White
GMP/Eugmp/Written Confirmation/ISO/Kosher
Avaliable
Avaliable
Air/Sea/Express
"ISO 9001, ISO 22000, ISO14001,OHSAS18001,FAMI-QS,
Drum
25kg/drum
China
2932999099
Product Description
Naringenin
CAS: 480-41-1
CAS: 480-41-1
Chemical name: (+/-)-4'',5,7-Thihyydroxy flavanone; (+/-)-naringenin; naringetol
Molecular formula: C15H12O5
Molecular wight: 272.25
CAS: 480-41-1
Appearance: white crystalline fine powder
Content: 98%
Analytical method: HPLC
Product original: Citrus paradis osbeck
Application: Naringenin is a potent inhibitor of the cytochrome p450 liver enzymes: CYP1A2, CYP3A3 and CYP3A4. There is however, considerable inter-individual variability in the effects of grapefruit juice on drug metabolism, in part due to 1) amount of naringenin formed by an individual, 2) amount of naringin present in a brand of grapefruit juice, 3) dilution of grapefruit juice used, and 4) other substances in grapefruit juice accounting for the interaction.2 Researchers at the University of Western Ontario in London discovered, while using various juices to hide the taste of a test substance given to patients along with their drugs as part of a cancer trial, that there was a synergistic or more effective action of the drug to breast cancer when it was given with Grapefruit Juice. From here, researchers launched studies of other fruits to find out why, and this is what they discovered. Human breast cancer cells in test tubes that were estrogen-insensitive; that is, the cells did not need estrogen to cock and prime them into maligency, respond well to a flavonoid found in grape juice, naringenin. Naringenin proved almost 8 times more potent at halting breast cancer cells's growth than another flavonoid, genestein from soy beans.
Our manufacturer has introduced ISO9001 quality management system certification, realizing the whole process control through product design, raw
material procurement, production process, quanlity assurance, product sales to after service;
Our manufacturer has fully implemented GMP/FDA/CEP management, GMPDA/CEP certifications are available.
Our manufactuer always takes innovation as the core, and attaches great importance to the improvement of its R & D comprehensive strength.
material procurement, production process, quanlity assurance, product sales to after service;
Our manufacturer has fully implemented GMP/FDA/CEP management, GMPDA/CEP certifications are available.
Our manufactuer always takes innovation as the core, and attaches great importance to the improvement of its R & D comprehensive strength.
1. We can offer you sample for testing.
2. We can pack the material as per your requirement.
3. We can provide you TP documents along shipment.
4. We can accept your audit if necessary near future.
5. We can offer the material as per your specification.
6. We can customize the product as per your specification.
7. We can arrange shipment professional and efficient.
2. We can pack the material as per your requirement.
3. We can provide you TP documents along shipment.
4. We can accept your audit if necessary near future.
5. We can offer the material as per your specification.
6. We can customize the product as per your specification.
7. We can arrange shipment professional and efficient.
