Frazer Supply CAS 154992-24-2 Hair Treatment Powder Ru58841 Ru 58841 Ru-58841

OC-000459; OC 000459;[5-Fluoro-2-methyl-3-(2-quinolinylmethyl)-1H-indol-1-yl]acetic acid;5-Fluoro-2-methyl-3-(2-quinolinylmethyl)-1H-indole-1-acetic acid.

OC-000459 for the treatment of hair loss dwindled, perhaps due more to commercial potential and chemical stability reasons than efficacy as the later studies of OC000459 have focused on different chemical forms of the drug and combining it with various nanoparticles to enhance delivery. Recent years have seen the odd study pop up in relation to OC000459 and the treatment of acne and prostate cancer, which are conditions also driven by, however, the most recent study published in relation to OC000459 was back in 2008.

OC000459 is a non-steroidal anti-androgen drug, which competes with DHT for binding at the receptors where it causes hirsutism or hair loss. It has been evaluated as being approximately equivalent in strength to hydroxyflutamide, a drug which is sometimes used in PCOS to treat hirsutism or androgenetic alopecia.

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