Crospovidone (PVPP) Used for Disintegrating Agent

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Shanghai Dexiang Medicine Tech. Co., Ltd.

VIP   Audited Supplier 15 years
Profile Certified by SGS/BV
DX-PVPP
Yes
Non-Customized
ISO 9001, USP, BP
Solid
95%
White Powder
Insoluble Pvp
[C6h9no)N
DX
20kgs/Drum
Bp/Ep/Usp
China
39059900
Product Description
Crospovidone (PVPP) Used for Disintegrating Agent
CTFAName: Polyplasdone, PVPP
CAS NO: 25249-54-1

Physical Properties:
exists as white or slight yellow, free flowing hygroscopic power with odourless or faint characteristic smell. It's insoluble in water, alkali, acid and common organic reagents Stereoscan photographs show that it is voluminous particulars and has large total surface and lots of porosity which is between 2-10nm. It can swell in water easily and can complex with polyphenol, carboxylic acids and other low molecular weight compounds. PVPF can only be used once and PVPR can be reused after regenerated.
 
PVPP CLPharm GradeFood Grade
AppearanceWhite or yellowish-white powder or flakes
Water-soluble substances    % max.1.51.5
pH Value (1% in water)5.0-8.05.0-11
Loss on Drying     % max5.06.0
Sulphate ash  % max0.10.1
Nitrogen Cotent    %11.0-12.811.0-12.8
ImpurityA(Vinylpyrrolidone)  ppm max1010
Peroxide(As H2O2)  ppm max4001000
Heavy metals     ppm max1010
Partical size (µm),  ≥80%50-25050-150

Package:







Applications
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To assure the effectiveness of the medicine,tablets and capsules are required to disintegrate within a certain time,if different adding methods of the disintegrating agent are used,the different disintegrating and dissolution speeds witll be achieved.PolyKoVidone is regarded as the top disintegrating agent thanks to its excellent swelling characteristics after the absoption of moisture.

                                                       
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