Polyvinylpyrrolidone Cross Linked Powder USP42

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Shanghai Dexiang Medicine Tech. Co., Ltd.

VIP   Audited Supplier 15 years
Profile Certified by SGS/BV
25249-54-1
ISO9001
Medicine Grade
Chemical Reagent
Solid
Not Volatile
White Powder
DX
25kgs/Drum
Bp/Ep/Usp
China
39059900
Product Description

Product Name:Crospovidone

Chemical Description:Croslinked PVP,Crospovidone,Insoluble PVPPollyvinylpolypyrrolidone

INCI/CTFA:Insoluble PVP

Pharmacopeia Name:Crospovidone (Crospovidonum)

CAS NO.:9003-39-8,25249-54-1

Formula Structure:

Product Properties: Crospovidone is hygroscopic,insoluble in water and all other common solvents,but it swells rapidly in aqueous solutbition without any gel froms.Its; classified as Crospovidone Type A and Type B according to the different particle size.

 

Specifications:

Product

Crospovidone Type A

Crospovidone Type B

Appearance

White or yellowish-white powder or flakes

Identifications

Meet ID Tests

Solubility

Practically insoluble in water,in alcohol and in methylene chloride

Water- soluble substances

1.0% max

1.0% max

pH((1% in water)

5.0 -8.0

5.0 -8.0

Loss on Drying

5.0% max.

5.0% max.

Sulphated Ash

0.1% max.

0.1% max.

Nitrogen content

11.0 -12.8 %

11.0 -12.8 %

Impurity A

10 ppm max.

10 ppm max.

Peroxide(As H2O2)

400 ppm max.

1000 ppm max.

Heavy Metal

10 ppm max.

10 ppm max.

Particle Size(μm), ≥80%

50-300

5-50

 

Applications:

In the pharmaceutical industry,Crospovidone are widely used as

1)Disintergrating agent,

2)Stabilizer for suspension,

3)Moisture Absorbent,

4)Complextant of Polyphenols and Tannin for the extract formulations.

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