Audited Supplier
Product Name:Crospovidone
Chemical Description:Croslinked PVP,Crospovidone,Insoluble PVPPollyvinylpolypyrrolidone
INCI/CTFA:Insoluble PVP
Pharmacopeia Name:Crospovidone (Crospovidonum)
CAS NO.:9003-39-8,25249-54-1
Formula Structure:
Product Properties: Crospovidone is hygroscopic,insoluble in water and all other common solvents,but it swells rapidly in aqueous solutbition without any gel froms.Its; classified as Crospovidone Type A and Type B according to the different particle size.
Specifications:
Product | Crospovidone Type A | Crospovidone Type B |
Appearance | White or yellowish-white powder or flakes | |
Identifications | Meet ID Tests | |
Solubility | Practically insoluble in water,in alcohol and in methylene chloride | |
Water- soluble substances | 1.0% max | 1.0% max |
pH((1% in water) | 5.0 -8.0 | 5.0 -8.0 |
Loss on Drying | 5.0% max. | 5.0% max. |
Sulphated Ash | 0.1% max. | 0.1% max. |
Nitrogen content | 11.0 -12.8 % | 11.0 -12.8 % |
Impurity A | 10 ppm max. | 10 ppm max. |
Peroxide(As H2O2) | 400 ppm max. | 1000 ppm max. |
Heavy Metal | 10 ppm max. | 10 ppm max. |
Particle Size(μm), ≥80% | 50-300 | 5-50 |
Applications:
In the pharmaceutical industry,Crospovidone are widely used as
1)Disintergrating agent,
2)Stabilizer for suspension,
3)Moisture Absorbent,
4)Complextant of Polyphenols and Tannin for the extract formulations.
