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Factory Supply API Raw Powder CAS 64485-93-4 Cefotaxime Sodium| Product name:Cefotaxime sodium |
| Other Name: Cefotaxime sodium salt |
| Appearance:White Powder |
| CAS:64485-93-4 |
| M.F:C16H16N5NaO7S2 |
| M.W.:477.45 |
| Specification:99% |
Cefotaxime Sodium is a third-generation semi-synthetic cephalosporin. It is not as effective against Gram-positive bacteria as cefazolin. Enterococcus is resistant to this product. It is not effective against penicillin-resistant pneumococci. It has a strong effect on Gram-negative bacteria. Bactericidal activity, antibacterial effect against Escherichia coli, influenza bacillus, Klebsiella pneumoniae, Proteus mirabilis, Salmonella is stronger than cefoperazone, weak or resistant to Bacteroides fragilis, Pseudomonas aeruginosa, Enterobacter cloacae Product is not sensitive..
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| ITEM | SPECIFICATION | RESULT | METHOD |
| Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual |
| Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
| Specific Optical | -2.4°~ -2.8° | -2.72° | |
| Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
| Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
| Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
| Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
| Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
| pH | 4.5~7.0 | 5.10 | |
| Related substance | Spot not bigger than standard solution spot | No spot | TLC |
| Water Content | ≤2% | 0.26% | KF |
| Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
| Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
Cefotaxime Sodium is used for infection of respiratory tract, urinary tract, bones and joints, skin and soft tissues, abdominal cavity, biliary tract, digestive tract, facial features, genitals, etc. caused by sensitive bacteria, infection caused by burns and trauma, and sepsis, central The infection is also effective.
