Pharmaceutical Raw Lumefantrine Artemether Lumefantrine Powder Lumefantrine| Product name:Lumefantrine |
| Other Name: Benflumentol |
| Appearance:Light Yellow Powder |
| CAS:82186-77-4 |
| M.F:C30H32Cl3NO |
| M W:528.94 |
| Grade:Pharmaceutical Grade |
| Specification:99% |
Lumefantrine (or benflumetol) is an antimalarial pharm. It is only used in combination with artemether.The term "co-artemether" is sometimes used to describe this combination. Lumefantrine has a much longer half-life compared to artemether, and is therefore thought to clear any residual parasites that remain after combination treatment.
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| ITEM | SPECIFICATION | RESULT | METHOD |
| Appearance | Light Yellow powder, neutral odor, highly hygroscopic | Conforms | Visual |
| Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
| Specific Optical | -2.4°~ -2.8° | -2.72° | |
| Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
| Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
| Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
| Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
| Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
| pH | 4.5~7.0 | 5.10 | |
| Related substance | Spot not bigger than standard solution spot | No spot | TLC |
| Water Content | ≤2% | 0.26% | KF |
| Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
| Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
It can reduce the gametophyte rate in blood, suppression the development of the gametophyte in mosquitoes.The cure rate of chloroquine-resistant and multidrug-resistant falciparum malaria is more than 95%.Animal experiments show that the toxicity of this product is very low, and no adverse reaction on the clinical.


















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