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Kava Extract
QINGYA
1kg/Bag; 15kg/Carton; 25kg/Drum
10% 20% 30% 50% 70%
China
1302199099
Product Description
Product physical and chemical properties
| Product name: Kavalactone Kava Extract |
| Extraction source: leaf |
| Active Ingredient: Kavalactone 10% 20% 30% 50% 60% 70% |
| Chemical formula:C14H16O3 |
| Molecular weight:232.27504 |
| CAS No.:9000-38-8 |
| Appearance: Yellow Powder |
| Extraction method: HPLC |
| Solubility: Insoluble in water, easily soluble in organic solvents. |
| Packaging specification: 25kg/Drum, customized packaging according to customer requirements |
| Storage method: Keep in a cool and dry place, away from light, use as soon as possible after opening. |
Kavalactone Product Description:
Kava pepper is a perennial shrub of the pepper family. In some regions of Africa, the roots of Kava pepper and the wine it produces are collectively referred to as "Kava" (Kawax). Kava is a popular herb for treating anxiety, considered non addictive or relatively non-toxic. In 1995, Kava pepper became one of the top 20 best-selling herbs in Germany. At the same time, Kava extract and its products were sold in numerous health food stores or by mail order in the United States, and now have entered supermarket shelves.
Kava pepper is a perennial shrub of the pepper family. In some regions of Africa, the roots of Kava pepper and the wine it produces are collectively referred to as "Kava" (Kawax). Kava is a popular herb for treating anxiety, considered non addictive or relatively non-toxic. In 1995, Kava pepper became one of the top 20 best-selling herbs in Germany. At the same time, Kava extract and its products were sold in numerous health food stores or by mail order in the United States, and now have entered supermarket shelves.
Kavalactone Main component :
The main active ingredients in kava pepper are fat-soluble resins, most of which are α-pyranone derivatives, namely kava lactones: Anesthetic capsicin (Methysticin), dihydrogen capsicin, drunken capsicin, methoxy capsicin that is, sheep gaoxin, dihydrogen anesthetic capsicin, demethoxy sheep gaoxin, 5, 6-dehydrogenated anesthetic capsicin, 11-methoxy-normethoxyinein and so on. There are also p-methoxycarvanine, sheep gaunine dimer, and demethoxysheep gaunine dimer.
The main active ingredients in kava pepper are fat-soluble resins, most of which are α-pyranone derivatives, namely kava lactones: Anesthetic capsicin (Methysticin), dihydrogen capsicin, drunken capsicin, methoxy capsicin that is, sheep gaoxin, dihydrogen anesthetic capsicin, demethoxy sheep gaoxin, 5, 6-dehydrogenated anesthetic capsicin, 11-methoxy-normethoxyinein and so on. There are also p-methoxycarvanine, sheep gaunine dimer, and demethoxysheep gaunine dimer.
Kavalactone Efficacy:
1. Nervous system function
(1) Anti-anxiety effect: cavanolactone can improve the attention, memory and responsiveness of anxiety patients, so that patients are in a relaxed state, but its effect is slow. Jena University in Germany conducted a controlled experiment on 101 outpatients suffering from anxiety and obsessive-compulsive neurosis, patients were given 100mg/ day kava extract and placebo, 8 weeks later, kava group patients have significant effects.
(2) Sedative and hypnotic effect: intravenous or oral administration of dihydropachycapillin or dihydroanesthetic pachycapillin has sedative and hypnotic effect on mice, rats, rabbits and cats, and can cause ataxia and normal reflex disappearance at high doses. It is thought that kava pyranones may act through GABA receptor binding sites.
(3) Local anesthetic effect: Kava extract can cause muscle paralysis, local anesthetic effect on experimental frogs, paralyze the wings of bats and sparrows. The mechanism of action is similar to that of lidocaine, which acts by blocking potential dependent sodium channels.
2. Antifungal effects Kava piperanone has no inhibitory effect on the growth of gram-positive or gram-negative bacteria. Some kavapyrones have significant inhibitory effect on many fungi, including some human pathogens.
3. Muscle relaxation effects All kinds of kava piperopyranone have a muscle relaxation effect on all kinds of experimental animals, and it is more effective than Mephenesin in protecting mice against convulsive and lethal effects
4. Other effects Kava extract also has diuretic effect and antithrombotic effect.
1. Nervous system function
(1) Anti-anxiety effect: cavanolactone can improve the attention, memory and responsiveness of anxiety patients, so that patients are in a relaxed state, but its effect is slow. Jena University in Germany conducted a controlled experiment on 101 outpatients suffering from anxiety and obsessive-compulsive neurosis, patients were given 100mg/ day kava extract and placebo, 8 weeks later, kava group patients have significant effects.
(2) Sedative and hypnotic effect: intravenous or oral administration of dihydropachycapillin or dihydroanesthetic pachycapillin has sedative and hypnotic effect on mice, rats, rabbits and cats, and can cause ataxia and normal reflex disappearance at high doses. It is thought that kava pyranones may act through GABA receptor binding sites.
(3) Local anesthetic effect: Kava extract can cause muscle paralysis, local anesthetic effect on experimental frogs, paralyze the wings of bats and sparrows. The mechanism of action is similar to that of lidocaine, which acts by blocking potential dependent sodium channels.
2. Antifungal effects Kava piperanone has no inhibitory effect on the growth of gram-positive or gram-negative bacteria. Some kavapyrones have significant inhibitory effect on many fungi, including some human pathogens.
3. Muscle relaxation effects All kinds of kava piperopyranone have a muscle relaxation effect on all kinds of experimental animals, and it is more effective than Mephenesin in protecting mice against convulsive and lethal effects
4. Other effects Kava extract also has diuretic effect and antithrombotic effect.
