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Description
Sodium butyrate is a compound with formula Na(C3H7COO). It is the sodium salt of butyric acid. It has various effects on cultured mammalian cells including inhibition of proliferation, induction of differentiation and induction or repression of gene expression. As such, it can be used in lab to bring about any of these effects. Specifically, butyrate treatment of cells results in histone hyperacetylation, and butyrate itself inhibits class I histone deacetylase (HDAC) activity, specifically HDAC1, HDAC2, HDAC3, and HDAC8. Butyrate has been an essential vehicle for determining the role ofhistone acetylation in chromatin structure and function. Inhibition of HDAC activity is estimated to affect the expression of only 2% of mammalian genes.
In the lab, sodium butyrate is usually found as a white, water-soluble, crystalline solid. The chemical is notable for having a very strong, unpleasant smell that lingers. When working with sodium butyrate, gloves, eye protection and respiratory masks are advised for safety purposes.
The compound is found in human diet, notably produced in large amounts from dietary fiber in the gut and present in Parmesan cheese and butter.Nevertheless, the most common source of sodium butyrate in the gut is from consumption of legumes, which along with fiber have been associated with delayed aging and healthspan.
Specification
| Check item | Specifications |
| Content | ≥99.0% |
| Loss on drying | ≤2.0% |
| Smelting point | 250.0-253.0ºC |
| Free acid | pass |
| Free alkalinity | pass |
| Total number of colony | <1000cfu/g |
| Saccharomycetes/mould | < 50cfu/g |
| Coliform | Feminine |
| PH(1% Solution ) | 6.0-9.0 |
| Heavy metals as pb | ≤0.0005% |
| As | ≤3PPM |
| Water -insoluble | ≤0.01% |
Package and shipment
Packing: Packages are 25kg/bag,Which can meet the different package requirement of customers
Shipping: EMS,DHL,By Sea ,etc.
A.M Factory
A.M Food Chemical Co., Ltd, a professional food additive, feed additive and pharm intermediate
manufacturer in China. With many years experience and supported by the company's strong technical
know-how and dedicated R&D facilities. All of our products used for food and feed industry meet or
exceed international quality standards
Inspection
Customers Visit
Each month, A.M Food Chemical is visited by many customers from different countries. They coming for
test our products, plants, designd and place the order in the office after negotiation. Welcome you to
come and test A.M products in person.
