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| Common Name | Tretinoin/Retinoic acid | ||
|---|---|---|---|
| CAS Number | 302-79-4 | Molecular Weight | 300.435 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 462.8±14.0 °C at 760 mmHg |
| Molecular Formula | C20H28O2 | Melting Point | 179-184ºC |
| MSDS | ChineseUSA | Flash Point | 350.6±11.0 °C |
TEM | SPECIFICATION | METHOD REFERENCE |
Appearance | orange yellow powder | Visual |
Ammonium | ≤200ppm | Glutathione USPmonograph |
Chloride | ≤200ppm | USP35<221> |
Sulfate | ≤300ppm | USP35<221> |
Iron | ≤10ppm | USP35<241> |
Arsenic | ≤2ppm | USP35<211> |
Heavy metals | ≤10ppm | USP35<231>Method I |
Loss on drying(3h at 105 ºC) | ≤0.5% | USP35<731> |
Residue on Ignition | ≤0.1% | USP35<281> |
Total impurities | ≤2.0% | Glutathione USP monograph |
Assay(dry basis) | 98.0% to 101.0% | Glutathione USP monograph |
Function
1.It is a drug commonly used to treat acne vulgaris and keratosis pilaris.
2.It is available as a cream or gel. It is also used to treat acute promyelocytic leukemia.
3.It can stimulate skin growth and keep epidermic normal.
4.It can slow down skin aging process for solarization, remove tiny wrinkles.
5.It can reduce skin roughness, so skin will become ruddy.
Application
1. Tretinoin is widely applied in pharmaceutical field, mainly used for the cure of dermatonosus like acne, ichthyosis and psoriasis abnormal, etc..
2. Tretinoin can be made into tretinoin or retinoic acid cream to cureacne or other unhealthy skin.
3. Tretinoin is used for skin keratinocytes-resistant drugs and cell-induced differentation drug.
Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
