Audited Supplier
| Product name | Tianeptine sodium salt |
| Assay | 99% |
| CAS No | 30123-17-2 |
| Packing | Customized package as you require |
| M.F. | C21H24ClN2NaO4S |
| M.W. | 458.93 |
| Appearance | White crystalline powder |
| Brand Name | Sendi |
| Quality Standard | Enterprise Standard |
| Usage | Treatment of depression. |
Tianeptine sodium is primarily used for its mood boosting and anti-anxiety properties. This substance also has nootropic abilities in regards to individuals whose cognition is negatively impacted by mood disorders. It has the ability to improve focus and concentration in individuals who have poor attention spans as well.
Depressive illness devastates millions of lives. Tianeptine is a neuroprotective antidepressant that reverses the neuronal damage and lasting misery caused by chronic, uncontrolled stress. Tianeptine acts both as a non-sedating anti-anxiety agent and a non-stimulating mood-brightener. Uniquely in clinical medicine, tianeptine acts as a selective serotonin reuptake enhancer. Its puzzling efficacy as an antidepressant illustrates how little modern psychiatric medicine really understands about mind, mood and depression.
Tianeptine is chemically a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Tianeptine shows efficacy against serious depressive episodes (major depression), comparable to amitriptyline, imipramine and fluoxetine, but with significantly fewer side effects. It was shown to be more effective than maprotiline in a group of people with co-existing depression and anxiety. Tianeptine also displays significant anxiolytic properties and is useful in treating a spectrum of anxiety disorders including panic disorder, as evidenced by a study in which those administered 35% CO2 gas (carbogen) on paroxetine or tianeptine therapy showed equivalent panic-blocking effects. Like many antidepressants (including bupropion, the selective serotonin reuptake inhibitors, the serotonin-norepinephrine reuptake inhibitors, moclobemide and numerous others) it may also have a beneficial effect on cognition in people with depression-induced cognitive dysfunction.
Specification:
| ANALYTICAL ITEMS | SPECIFICATION | ANALYTICAL RESULTS |
| Appearance | White to Off-White Powder | White powder |
| Color of solution | ≤Y7 | Confirms |
| Bulk Density (Untapped) | 0.90g/cm3~1.08g/cm3 | Confirms |
| pH | 7.5~9.0 | Confirms |
| Specific Rotation[α]25D | -2.4~2.95 | Confirms |
| Related Substances (HPLC) | G.P.E. :<0.2% | Confirms |
| Related Substances(TLC) | Single spot | Confirms |
| Loss on drying | ≤2.0% | 0.08% |
| Solvents Residue(Ethanols) | ≤1.0% | Confirms |
| Assay | >99.0% | 99.2% |
| Conclusion | Confirms to Enterprise Standard | |
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