Adenosine 5 Monophosphate 5′ -AMP Adenosine Monophosphate

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Allright GC (Jinan) Biotechnology Ltd.

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Adenosine Monophosphate
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Product Description



 

Adenosine 5 Monophosphate 5'-AMP Adenosine Monophosphate

 
 
Product NameAdenosine Monophosphate
Molecular Weight347.2
CAS NO61-19-8
Molecular FormulaC10H14N5O7P
 

Adenosine monophosphate (referred to as AMP), also known as adenosine monophosphate, 5'-adenine nucleotide or adenylate, is a ribonucleic acid (RNA) found in the nucleotide The It is an ester of phosphoric acid and nucleoside, and consists of phosphate functional groups, pentose glycans and base adenine. ATP is obtained by ATP hydrolysis twice. A base plus a five carbon sugar. Is deoxynucleotides or ribonucleotides depending on whether the five carbon sugar, there is no oxygen, has nothing to do with the base. RNA is one of the constituent units; also vitamin B8, a water-soluble vitamins.

 




Adenosine also plays a role in signalling various pathways and functions in the body by forming signally molecules like cyclic adenosine monophosphate (cAMP).   -In the brain adenosine is an inhibitory neurotransmitter. This means, adenosine can act as a central nervous system depressant. In normal conditions, it promotes sleep and suppresses arousal. When awake the levels of adenosine in the brain rise each hour.   -In the heart adenosine causes dilation of the coronary blood vessels that improves blood circulation to the heart. Adenosine also increases the diameter of blood vessels in the peripheral organs. -In the heart adenosine decreases heart rate and in blood it has an anti-platelet action. Antiplatelet action prevents platelet aggregation and coagulation. -In blood adenosine is broken down by adenosine deaminase. This enzyme is present in red cells and the vessel wall. The drug Dipyridamole is an inhibitor of the enzyme adenosine deaminase and thus raises the levels of adenosine in blood. This leads to blood vessel dilatation and improved blood flow through the coronary blood vessels that supply the heart muscles. -In the kidneys adenosine decreases renal blood flow and decrease the production of rennin from the kidneys. -In the lungs it causes constriction of airways and in the liver it leads to constriction of blood vessels and increases breakdown of glycogen to form glucose.

Adenosine is an endogenous nucleoside throughout the human cells directly into the myocardium by phosphorylation generates adenylate involved in myocardial energy metabolism. Adenosine also attend the expansion of coronary vessels, increasing blood flow.

 

Adenosine plays a physiological role on the cardiovascular system and the body's many systems and organizations. Adenosine is used in the synthesis adenosine triphosphate, adenosine (ATP), adenine, adenosine, the vidarabine important intermediates.

 

Mechanism

Adenosine plays an important role in biochemistry, including adenosine triphosphate (ATP) or adeno-bisphosphate (ADP) form of transfer of energy, or to cyclic adenosine monophosphate (cAMP) for signal transmission and so on. In addition, adenosine is an inhibitory neurotransmitter (inhibitory neurotransmitter), may promote sleep.

 

Academic Research

In the December 23 "natural - Medicine" (Nature Medicine) magazine, a new study shows that a compound will help us to alleviate the brain of sleep and other brain disease Parkinson's disease Deep brain stimulation of the success are crucial. This study shows that: a sleepy brain could lead to compound - Adenosine is a deep brain stimulation (DBS) effect of the key. The technology for the treatment of Parkinson's disease and patients with severe tremor, this method was also tried for the treatment of severe depression.

 

 


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