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Disodium Ethylenediaminetetraacetate (EDTA-2Na)
Chemical Formula: C10H14N2Na2O8.2H2O
CAS No.: 6381-92-6
Synonyms: EDTA disodium salt, EDTA-2Na
1. Basic Properties
| Property | Description |
|---|---|
| Appearance | White crystalline powder or granules |
| Solubility | Freely soluble in water (~100 g/L at 20°C), slightly soluble in ethanol |
| pH (1% solution) | 4.0-5.5 (weakly acidic) |
| Stability | Stable at room temperature; decomposes at >150°C |
| Chelating Capacity | Strong chelation of divalent metal ions (e.g., Ca²+, Mg²+, Fe²+) |
2. Key Applications
- 1.Food Industry:
- Preservative (E386): Inhibits metal ion-catalyzed oxidation to extend shelf life (e.g., canned foods, beverages).
- Color Stabilizer: Prevents enzymatic browning in fruits and vegetables.
- 2.Cosmetics:
- Stabilizer: Prevents metal ion-induced degradation in formulations (e.g., lotions, sunscreens).
- 3.Pharmaceuticals & Laboratories:
- Anticoagulant: Binds Ca²+ to prevent blood clotting in sample tubes.
- Buffer Component: Used in molecular biology (e.g., DNA extraction buffers).
- 4.Industrial Water Treatment:
- Scale Inhibitor: Softens water by sequestering Ca²+/Mg²+, preventing pipe scaling.
3. Technical Specifications (Industrial Grade)
| Parameter | Standard Value |
|---|---|
| Purity | ≥99% |
| Moisture | ≤0.5% |
| Heavy Metals (as Pb) | ≤10 ppm |
| Iron (Fe) | ≤5 ppm |
| Chelating Value (CaCO3) | ≥330 mg/g |
4. Safety & Storage
- Toxicity: Low toxicity (Oral LD50 in rats: 2,000-4,000 mg/kg). Prolonged exposure may disrupt mineral metabolism.
- Handling Precautions:
- Avoid dust inhalation (use dust masks).
- Rinse skin/eyes immediately upon contact.
- Storage Conditions:
- Keep sealed in a cool, dry place (<25°C, humidity <60%).
- Separate from strong oxidizers and acids.
- Shelf Life: 24 months (unopened).
5. Usage Guidelines
- Dissolution Method:
Gradually add to warm water (40-50°C) with stirring to avoid clumping. - Recommended Dosage:
- Food Additive: 0.01%-0.1% (of final product weight).
- Water Treatment: 0.1-1.0 g/L (adjust based on water hardness).
- Compatibility:
Compatible with most anionic/nonionic surfactants. Avoid direct mixing with strong oxidizers (e.g., H2O2).
6. Comparison with EDTA-4Na
| Property | EDTA-2Na | EDTA-4Na |
|---|---|---|
| Sodium Ions | 2 | 4 |
| Solubility | Lower (requires warm water) | Higher (soluble in cold water) |
| pH Suitability | Weakly acidic to neutral | Alkaline (pH 8-12) |
| Cost | Lower | Higher |
7. Regulatory Compliance
- Food Grade:
- China: GB 1886.100-2016
- EU: E386 (compliant with EC 1333/2008)
- USA: FDA 21 CFR §172.135
In the salts of ethylenediamine tetra acetic acid, two sodium salt is the most important. It is an important complexing agent. It is used for complexing metal ions and separating metals. It can also be used in detergents, liquid soap, shampoo, agricultural chemical spray, color photosensitive material, rinsing and processing bleaching fixative, water purifying agent, pH regulator, negative coagulant, etc. In the redox initiation system for SBR polymerization, EDTA disodium is used as an active agent to complex ferrous ions and control the polymerization reaction rate. The drug is low toxicity, and LD50 is 2000 mg / kg in rats. Used as a chelator for metal ions.
Check calcium, magnesium, etc. It is used in pharmaceutical industry, color development, smelting of rare metals and other fields. It is an important complexing agent and metal masking agent.
It is used as ammonia carboxycomplex for the determination of calcium, magnesium and other metals. It is used as metal masking agent and color developer. It is also used in pharmaceutical industry and smelting of rare metals.
It is also used as an antioxidant and a metal chelating agent, which has the same function as EDTA, but it has a wider application range. The cosmetics raw materials contain trace metal ions and can be used in the production and storage and transportation of cosmetics.
