High Quality/Purity 99%/CAS 119302-91-9/Muscle Relaxant/Ep-USP Grade GMP Certified/API/Rocuronium Bromide

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GYF BIOTECH LTD.

VIP   Audited Supplier 4 years
Profile Certified by SGS/BV
GYF-105
API
COA
119302-91-9
2
No
No
IPA
Wooden Barrel
25kg/Wooden barrel
China
2934999099
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119302-91-9 Rocuronium bromide  EP10/USP42 standard

ItemsStandardsResults
AppearanceOff-white to light yellow powder,hygroscopicityOff-white powder,
hygroscopicity
SolubilityFreely soluble in water,ethanol trichloromethane or glacial acetic acid,almost insoluble in ethercomplied
Specific rotation+28.5°to+32.0°+30.9°
Identification
(1)The retention time of test solution main peak should be accordance with system suitability test solution of Rocuronium Bromide peak.complied
(2)Identification reaction of bromide in aqueous solution of this productcomplied
(3)The infrared absorption of this product should be accordance with W.S spectrumcomplied
AlkalinityPH:8.9-9.59.3
Color and clarity of solutionThe solution should be colorless and clarified;If it appears color,should not be stronger than yellow or orange yellow No.2 standard colorimetric solution.complied
Acetic acidNot more than 0.5%N.D
3-BromopropeneIf there are chromatographic peaks with the same retention time as the main peak of the control solution,the peak area should not more than the main peak area of the reference solution(0.0005%)N.D


Related substances
 
Impurity A not more than 0.1%N.D
Impurity B not more than 0.2%0.06%
Impurity C not more than 0.2%0.01%
Impurity F not more than 0.1%0.01%
Impurity G not more than 0.1%N.D
Impurity H not more than 0.1%N.D
Other single impurity not more than 0.10%N.D
Total impurities should be not more than 1.0%0.087%
Residual solventsMethanol not more than 0.3%N.D
Ethyl ether not more than 0.5%0.2%
Acetone not more than 0.5%0.004%
Acetonitrile not more than 0.041%N.D
Dichloromethane not more than 0.06%N.D
Methyl tert-butyl ether not more than 0.5%0.02%
TriethylamineNot more than 0.032%N.D
Water contentNot more than 3.5%1.8%
Residue on ignitionNot more than 0.1%0.06%
Heavy metalNot more than 10ppmcomplied
Bacterial endotoxinEndotoxin amount per 1mg Rocuronium Bromide should be less than 0.3EUcomplied
Assay(calculate by anhydrous&solvent-free substances)99.0%-101.0%100.7%
ConclusionThis product is tested by Rocuronium Bromide(For export)quality standard(STP-11-338-01).
The results comply with(√Yes No).
The results comply with EP10.0 Rocuronium Bromide quality standard.



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