Audited Supplier
NY004
ISO, Halal
HPLC-MS, HPLC, UV
Injection, Capsule, Softgels, Tinctures, Liquids, Drops
Health Care Products, Medicine
Powder
Silybum Marianum Seed
3 Days
2.07%
0.43%
Yellowish-Brown Fine Powder
Nutrayours/ OEM
25kg/Drum
Silymarin&Silibinin
China
1302199099
Product Description
- 100% NATURAL PRODUCT: No artificial colors or flavors
- Verified herb identity, confirmed highest quality of raw materials and the extract
- Best natural sources of herbs and raw materials: Every vendor is carefully picked to meet our high standards
- Third-party lab tested, All natural Milk Thistle Extract
- Liver Cleanse Detox
Milk thistle (Silybum marianum) is a medicinal plant from the Asteraceae family. Silymarin is the major constituent of milk thistle extract and is a mixture of some flavonolignans such as silybin, which is the most active component of silymarin. It is most commonly known for its hepatoprotective effect.
| Contaminants | |||
| Arsenic (As) | ≤ 0.5 mg/kg | Conforms | GB 5009.76 |
| Lead (Pb) | ≤ 0.5 mg/kg | Conforms | GB 5009.75 |
| Mercury (Hg) | ≤ 0.1 mg/kg | Conforms | GB 5009.17 |
| Cadmium(Cd) | ≤ 0.5 mg/kg | Conforms | GB 5009.15 |
| Residual Acetone | ≤ 5,000 μg/g | 3.4x10³μg/g | USP42 |
| Residual Hexane | ≤ 290 μg/g | 16 μg/g | USP42 |
| Pesticide Residues | Meet Reg. (EC) No 396/2005 | Conforms | Reg. (EC) No 396/2005 |
| Microbiological | |||
| Total Plate Count | ≤ 1,000 cfu/g | Conforms | GB 4789.2 |
| Mold&Yeast | ≤ 100 cfu/g | Conforms | GB 4789.15 |
| E. Coli | <10 cfu/g | Conforms | GB 4789.38 |
| Salmonella | Absent/25g | Conforms | GB 4789.4 |
| Staphylococcus aureus | <10 cfu/g | Conforms | GB4789.10 |
| Irradiation status | Non irradiated, No ETO treated, Negative by PSL screen test. | ||
| GMO/BSE Status | Non-GMO, Free of BSE. | ||
* The statements in this section have not been evaluated by the FDA or EFSA.
References
1. Fallah M, Davoodvandi A, Nikmanzar S, et al. Silymarin (milk thistle extract) as a therapeutic agent in gastrointestinal cancer. Biomed Pharmacother. 2021;142:112024. doi:10.1016/j.biopha.2021.112024
2. Wang J, Zhang L, Cao H, et al. Silibinin improves L-cell mass and function through an estrogen receptor-mediated antioxidative mechanism. Phytomedicine. 2022;99:154022. doi:10.1016/j.phymed.2022.154022
3. Zheng N, Liu L, Liu WW, et al. Crosstalk of ROS/RNS and autophagy in silibinin-induced apoptosis of MCF-7 human breast cancer cells in vitro. Acta Pharmacol Sin. 2017;38(2):277-289. doi:10.1038/aps.2016.117
4. Wang J, Zhang X, Zhang L, et al. Silychristin A activates Nrf2-HO-1/SOD2 pathway to reduce apoptosis and improve GLP-1 production through upregulation of estrogen receptor α in GLUTag cells. Eur J Pharmacol. 2020;881:173236. doi:10.1016/j.ejphar.2020.173236
3. Zheng N, Liu L, Liu WW, et al. Crosstalk of ROS/RNS and autophagy in silibinin-induced apoptosis of MCF-7 human breast cancer cells in vitro. Acta Pharmacol Sin. 2017;38(2):277-289. doi:10.1038/aps.2016.117
4. Wang J, Zhang X, Zhang L, et al. Silychristin A activates Nrf2-HO-1/SOD2 pathway to reduce apoptosis and improve GLP-1 production through upregulation of estrogen receptor α in GLUTag cells. Eur J Pharmacol. 2020;881:173236. doi:10.1016/j.ejphar.2020.173236
